Seminar in SMMEE: Bone’s Adaptation to Mechanical Environment

Title: Bone’s Adaptation to Mechanical Environment
Speaker: Mr. Abhishek Kumar Tiwari, Research Scholar, SMMEE, IIT Ropar
Location: L2
Date: Friday,12th April 2012
Time: 4:15 pm

Abstract:
Bone adapts to mechanical environment. Metabolic bone disorders such as osteoporosis or bone/muscle disuse (as in individuals with a physical disability or after a prolonged spaceflight) cause bone loss, making bone more susceptible to fracture. Prevention and treatment of the loss is a major challenge. A few studies reported that mechanical loading of bone can prevent and cure such bone loss. In-vivo animal studies have also concluded that elevated mechanical strain in bone induces new bone formation.
However, the exact relationship between the mechanical environment and the new bone formation is not known. During the course of my talk I will discuss about the development of a computational model which will integrate the findings from in-vivo studies to fit available experimental data on loading-induced new bone formation. The model will also be inverted in future to predict the loading regimen required for a prescribed bone response. This model will bring advancement in relating the new bone formation to mechanical environment as well as being useful in identifying therapeutic
intervention, such as type of physical exercise required to prevent and treat bone loss

Speaker's bio-sketch: Mr. Abhishek Kumar Tiwari is a PhD scholar with the School of Mechanical, Materials and Energy Engineering at IIT Ropar. After completing his Bachelor of Technology degree in Mechanical Engineering from Uttar Pradesh Technical University, he joined IIT Ropar in August 2011 as a PhD student under supervision of Dr. Jitendra Prasad and Dr. Navin Kumar. Currently he is pursuing his PhD on “Computational Modeling of Bone’s Adaptation to Mechanical Environment”. His other areas of interest are orthopedic biomechanics, bone adaptation algorithms and bone fracture healing.