Peptide aggregation: from materials to diseases

Dr. Aseem Mishra, Wellcome Trust - DBT IA Early Career Fellow, Malaria Research Group, International Center for Genetic Engineering and Biotechnology (ICGEB), New Delhi, will give a seminar on "Peptide aggregation: from materials to diseases" at 10:00 am on Thursday, 13 March 2014, in Room L3.

This seminar is a part of Biomedical Engineering Seminar Series organized by the Biomedical Engineering program of the institute. The abstract of the talk and brief biodata of the speaker is appended below.

You are cordially invited to attend the seminar.

Abstract

Peptide aggregation: From materials to diseases

 

Aseem Mishra
Wellcome Trust - DBT IA Early Career Fellow
Malaria Research Group
International Centre for Genetic Engineering and Biotechnology (ICGEB)
Aruna Asaf Ali Marg, New Delhi - 110067

 

Peptides have diverse biological roles in living systems from being active signalling molecules to components of defence mechanism. In the last few decades they have emerged as causative agents for few debilating degenerative disorders wherein they aggregate to form insoluble structures within the biological system. The same ability of these peptides has also been utilised to generate structures that can be used for drug-delivery applications due to their extreme biocompatibility. I will attempt to highlight my decade long research in in these areas.

 

About the speaker
Dr. Aseem Misra is a Wellcome Trust - DBT IA Early Career Fellow in Malaria Research Group at the International Center for Genetic Engineering and Biotechnology (ICGEB), New Delhi. He earned his PhD degree in Biotechnology at Jawaharlal Nehru University (JNU), New Delhi in 2009. Immediately after his PhD, he received the Wellcome Trust - DBT IA Early Career Fellowship and joined his current position in January 2010. He has worked as a Senior Research Fellow at the International AIDS Vaccine Initiative - Neutralizing Antibody Consortium from May 2009 to November 2009 and as a visiting Senior Research Fellow at the Department of Biological Sciences, National University of Singapore, Singapore from August 2012 to February 2013. In addition to Wellcome Trust award, he is a recipient of CRK Krishnamurthy Memorial Young Scientist and Ranbaxy Science Scholar awards. Dr. Mishra has about four years of research experience in deciphering mechanisms by which proteins/peptides aggregate and illicit cytopathic responses. He has used various strategies and state-of-the-art techniques to quantitate interactions of amyloidogenic peptides (hIAPP) with model and cellular membranes. He has also designed peptides that can modulate/inhibit these aggregations. He has published about 10 research articles in peer-reviewed international journals and is a co-inventor on 2 Indian patents.